Contributes to the education of scientists qualified for developing both basic and applied research.

Investigation Areas

Multidisciplinary Research

Nanoscience and nanotechnology study the phenomenon and manipulation of materials at the atomic, molecular and macromolecular scales, at which properties differ substantially from those observed at larger scales. Its scope extends to the full spectrum of the sciences and includes fields like medicine, physics, engineering, and chemistry. Owing to their applications, these disciplines constitutes important motors of the new industry and the knowledge society.

Packaging Technology

This group develops plastic films with nanocompounds to control the permeability of gases suited to the requirements of the food products that are packaged, and to develop active packaging with different activities, such as antimicrobial, antioxidant, ethylene and oxygen remover, in order to put safer products on the market, with longer life and added value. So, the purpose is to incorporate into plastic films nano-active substances based on silver, copper, titanium dioxide, modified zeolites and clays to control the oxygen, vapor pressure and ethylene flow between the container and the surrounding atmosphere. With these properties, this research line want to improve the shelf life of the food products packaged in this way. So, these studies consider the development of the appropriate nanoparticles, the way to incorporate them into the plastic film, the measurement of the properties of the film, and the determination of the improvement of these new materials as compared to traditional materials.



  1. A. Pereira; J. Escrig; J.L. Palma; C. López de Dicastillo; C. Patiño; M.J. Galotto
    Magnetic nanotubes obtained from atomic layer deposition coated electrospun nanofibers
    Journal of Vacuum Science & Technology B 36, 061803 (2018)
  2. N. Alvarado, J. Urdaneta, J. Romero, C. López de Dicastillo, M. Schmidt, M.J. Galotto, A. Guarda
    Improvement of physicochemical properties of starch films by blending it with poly(N-Vinyl-2-pyrrolidone)
    J Food Sci Nutr 2018, 4: 036
  3. P.A. Ulloa, J. Vidal, C. Lopéz de Dicastillo, F. Rodriguez, A. Guarda, R.M.S. Cruz, M.J. Galotto
    Development of poly(lactic acid) films with propolis as a source of active compounds: Biodegradability, physical, and functional properties
    Inc. J. Appl. Polym. Sci. 2018, 135, 47090
  4. C. López de Dicastillo, C. Patiño, M.J. Galotto, J.L. Palma, D. Alburquenque, J. Escrig
    Novel Antimicrobial Titanium Dioxide Nanotubes Obtained through a Combination of Atomic Layer Deposition and Electrospinning Technologies
    Nanomaterials 2018, 8(2), 128
  5. M.P. Arrieta, C. López de Dicastillo, L. Garrido, K. Roa, M.J. Galotto
    Electrospun PVA fibers loaded with antioxidant fillers extracted from Durvillaea antarctica algae and their effect on plasticized PLA bionanocomposites
    European Polymer Journal 103 (2018) 145-157
  6. A. Rojas, A. Torres, A. Añazco, C. Villegas, M.J. Galotto, A. Guarda, J. Romero
    Effect of pressure and time on scCO2-assisted incorporation of thymol into LDPE-based nanocomposites for active food packaging
    Journal of CO2 Utilization 26 (2018) 434-444
  7. C. López de Dicastillo, C. Villegas, L. Garrido, K. Roa, A. Torres, M.J. Galotto, A. Rojas, J. Romero
    Modifying an Active Compound’s Release Kinetic Using a Supercritical Impregnation Process to Incorporate an Active Agent into PLA Electrospun Mats
    Polymers 2018, 10, 479


  1. P.A. Ulloa,A. Guarda, X. Valenzuela, J.F. Rubilar, M.J. Galotto
    Modeling the release of antimicrobial agents (thymol and carvacrol) from two different encapsulation materials
    Food Sci Biotechnol (2017) 26(6):1763–1772
  2. C. López de Dicastillo, F. Bustos, X. Valenzuela, G. López-Carballo, J.M. Vilariño, M.J. Galotto
    Chilean berry Ugni molinae Turcz. fruit and leaves extracts with interesting antioxidant, antimicrobial and tyrosinase inhibitory properties
    Food Research International 102, 119-128
  3. N. Alvarado, J. Romero, A. Torres, C. López de Dicastillo, A. Rojas, M.J. Galotto, A. Guarda
    Supercritical impregnation of thymol in poly(lactic acid) filled with electrospun poly(vinyl alcohol)-cellulose nanocrystals nanofibers: Development an active food packaging material
    Journal of Food Engineering 217, 1-10
  4. A. Rojas, A. Torres, F. Martínez, L. Salazar, C. Villegas, M.J. Galotto, A. Guarda, J. Romero
    Assessment of kinetic release of thymol from LDPE nanocomposites obtained by supercritical impregnation: Effect of depressurization rate and nanoclay content
    European Polymer Journal 93 (2017) 294-306
  5. R.L. Abarca, F.J. Rodríguez, A. Guarda, M.J. Galotto, J.E. Bruna, M.A. Fávaro Perez, F. Ramos Souza Felipe, M. Padula
    Application of β-Cyclodextrin/2-Nonanone Inclusion Complex as Active Agent to Design of Antimicrobial Packaging Films for Control of Botrytis cinerea
    Food Bioprocess Technol (2017) 10: 1585
  6. M.P. Junqueira-Gonçalves, G.E. Salinas, J.E. Bruna, K. Niranjan
    An assessment of lactobiopolymer-montmorillonite composites for dip coating applications on fresh strawberries
    J. Sci. food Afric. 2017; 97: 1846-1853
  7. C. Villegas, A. Torres, M. Ríos, A. Rojas, J. Romero, C. López de Dicastillo, X. Valenzuela, M.J. Galotto, A. Guarda
    Supercritical impregnation of cinnamaldehyde into polylactic acid as a route to develop antibacterial food packaging materials
    Food Research International (2017) 99, 650-659
  8. C. López de Dicastillo, K. Roa, L. Garrido, A. Pereira, M.J. Galotto
    Novel Polyvinyl Alcohol/Starch Electrospun Fibers as a Strategy to Disperse Cellulose Nanocrystals into Poly(lactic acid)
    Polymers 2017, 9(4), 117 | Published 7 April
  9. C. López de Dicastillo, L. Garrido, N. Alvarado, J. Romero, J.L. Palma, M.J. Galotto
    Improvement of Polylactide Properties through Cellulose Nanocrystals Embedded in Poly(Vinyl Alcohol) Electrospun Nanofibers
    Nanomaterials 2017, 7(5), 106 | Published 11 May
  10. C. López de Dicastillo, J. Bruna, A. Torres, N. Alvarado, A. Guarda, M.J. Galotto
    A traditional aboriginal condiment as an antioxidant agent in the development of biodegradable active packaging
    J. Appl. Polym. Sci. 2017, 44692 | Published 15 April
  11. A. Torres, E. Ilabaca, A. Rojas, F. Rodríguez, M.J. Galotto, A. Guarda, C. Villegas, J. Romero
    Effect of processing conditions on the physical, chemical and transport properties of polylactic acid films containing thymol incorporated by supercritical impregnation
    European Polymer Journal 89 (2017) 195–210 | Published April


  1. C. López de Dicastillo, F. Bustos, A. Guarda, M.J. Galotto
    Cross-linked methyl cellulose films with murta fruit extract for antioxidant and antimicrobial active food packaging
    Food Hydrocolloids 60 (2016) 335-344; Published Oct 2016
  2. R.L. Abarca, F.J. Rodríguez, A.Guarda, M.J. Galotto, J.E. Bruna
    Characterization of beta-cyclodextrin inclusion complexes containing an essential oil component
    Food Chemistry 196 (2016) 968–975; Published 1 April 2016
  3. C. Hause, A. Peñaloza, A. Guarda, M.J. Galotto, J.E. Bruna, F.J. Rodríguez
    Development of an Active Packaging Film Based on a Methylcellulose Coating Containing Murta (Ugni molinae Turcz) Leaf Extract
    Food Bioprocess Technol (2016) 9: 298; Published Feb 2016
  4. C. López de Dicastillo, F. Rodríguez, A. Guarda, M.J. Galotto
    Antioxidant films based on cross-linked methyl cellulose and native Chilean berry for food packaging applications
    Carbohydrate Polymers 136 (2016) 1052–1060; Published 20 Jan 2016
  5. A. Vega-Gálvez, R. Díaz, J. López, M.J. Galotto, J.E. Reyes, M. Perez-Wona, L. Puente-Díaz, K. Di Scala
    Assessment of quality parameters and microbial characteristics of Cape gooseberry pulp (Physalisperuviana L.) subjected to high hydrostatic pressure treatment
    Food and Bioproducts Processing 97 (2016) 30–40; Published Jan 2016


  1. J.E. Bruna, H. Quilodrán, A. Guarda, F. Rodríguez, M.J. Galotto, P. Figueroa
    Development of antibacterial MtCu/PLA nanocomposites by casting method for potential use in food packaging
    J. Chil. Chem. Soc., 60, Nº 3 (2015); Published Sep 2015
  2. A. Rojas, D. Cerro,A. Torres, M.J. Galotto, A. Guarda, J. Romero
    Supercritical impregnation and kinetic release of 2-nonanone in LLDPE films used for active food packaging
    J. of Supercritical Fluids 104 (2015) 76–84; Published Sep 2015
  3. C. López de Dicastillo, R. Navarro, A. Guarda and M.J. Galotto
    Development of Biocomposites with Antioxidant Activity Based on Red Onion Extract and Acetate Cellulose
    Antioxidants 2015, 4(3), 533-547; Published 3 Aug 2015
  4. F.J. Rodríguez, L.A. Cortes, A. Guarda, M.J. Galotto, J.E. Bruna
    Characterization of cetylpyridinium bromide-modified montmorillonite incorporated cellulose acetate nanocomposite films
    J Mater Sci (2015) 50:3772–3780; Published May 2015
  5. A. Torres, C. Ramírez, J. Romero, G. Guerrero, X. Valenzuela, A. Guarda, M.J. Galotto
    Experimental and theoretical study of bisphenol A migration from polycarbonate into regulated EU food simulant
    Eur Food Res Technol 240:335–343; Published Feb 2015


  1. A. Torres, C. López de Dicastillo, M. Ríos, I. Bastias, A. Guarda, M.J. Galotto
    Effect of organoclay incorporation on thermal, physical and morphological properties of LLDPE nanocomposites for active food packaging applications
    J. Chil. Chem. Soc. [online]. 2014, vol.59, n.4, pp.2681-2685; Published Dec 2014
  2. J. López, A. Vega, M. J. Galotto
    High hydrostatic pressure on chemical composition, colour, phenolic acids and antioxidant capacity of Cape gooseberry pulp (Physalis peruviana L.)
    Food Science and Technology 58, 519-526
  3. A. Coloma, F. Rodríguez, J. Bruna, A. Guarda, M. J. Galotto
    Development of an active film with natural zeolite as ethylene scavenger
    Journal of the Chilean Chemical Society 59, 2409-2414
  4. F. J. Rodríguez, A. Torres, A. Peñaloza, H. Sepúlveda, M. J. Galotto, A. Guarda and J. Bruna
    Development of an antimicrobial material based on a nanocomposite cellulose acetate film for active food packaging
    Food Additives & Contaminants 31 (3), 342-353
  5. C. Hauser, A. Peñaloza, F. Rodríguez, A. Guarda, M. J. Galotto
    Promising antimicrobial and antioxidant extracts of Murta leaves (Ugni molinae Turcz): Shelf-life extension and food safety
    Food Packaging and Shelf Life 1, 77-85
  6. A. Torres, J. Romero, A. Macan, A. Guarda, M. J. Galotto
    Near critical and supercritical impregnation and kinetic release of thymol in LLDPE films used for food packaging
    J. of Supercritical Fluids 85, 41-48
  7. J. E. Bruna, M. J. Galotto, A. Guarda, F. Rodriguez
    A novel polymer based on MtCu2+/cellulose acetate with antimicrobial activity
    Carbohydrate polymers 102, 317-323


  1. R. Quintero, F. Rodríguez, A. Guarda, M. J. Galotto
    Characterization of antimicrobial cellulose acetate butyrate/organoclay nanocomposites
    Packaging Technology and Science (DOI 10.1002/pts.2043)
  2. L. Vidal J., M. Avello L., C. Loyola C., J. Campos P., P. Aqueveque M., S.R. Dungan, M.J. Galotto L., and A. Guarda M.
    Microencapsulation of maqui (Aristotelia chilensis [Molina] Stuntz) leaf extracts to preserve and control antioxidant properties
    Chilean Journal of Agricultural Research 73, 17-23
  3. R. Quintero, F.J. Rodríguez, J. Bruna, A. Guarda and M.J. Galotto
    Cellulose acetate butyrate nanocomposites with antimicrobial properties for food packaging
    Packaging Technology and Science 26, 249-265
  4. F.J. Rodríguez, H. Sepúlveda, J. Bruna, A. Guarda and M.J. Galotto
    Development of cellulose eco-nanocomposites with antimicrobial properties oriented for food packaging
    Packaging Technology and Science 26, 149-160
  5. F. Bobadilla, C. Rodríguez-Tirado, M. Imarai, M.J. Galotto, R. Andersson
    Soluble β-1,3/1,6 – glucan in seaweed from the southern hemisphere and its immunomodulatory effect
    Carbohydrate Polymers 92, 241-248


  1. M.J. Galotto, X. Valenzuela, F.J. Rodríguez, J. Bruna, A. Guarda
    Evaluation of the effectiveness of a new antimicrobial active packaging for fresh atlantic salmon (Salmo Salar L.) shelf life.
    Packaging Technology and Science, 25, 363-372
  2. A. Torres, A. Guarda, N. Moraga, J. Romero, M.J. Galotto
    Experimental and theorical study of thermodynamics and transport properties of multilayer polymeric food packaging
    European Food Research and Technology, 234, 713-722
  3. F.J. Rodríguez, A. Coloma, M.J. Galotto, A. Guarda, J. Bruna
    Effect of organoclay content and molecular weight on cellulose acetate nanocompposites properties
    Polymer Degradation and Stability, 97, 1996-2001
  4. F.J. Rodríguez, M.J. Galotto, J. Bruna and A. Guarda
    Modification of Cellulose Acetate Films Using Nanofillers Based on Organoclays
    Journal of Food Engineering 110, 262-268
  5. J.E. Bruna, A. Peñaloza, A. Guarda, F.J. Rodríguez and M.J. Galotto
    Development of LDPE 1 / MMTCu2+ nanocomposites with antimicrobial activity for potential use in food packaging
    Applied Clay Science 58, 79-87


  1. M.J. Galotto, A. Torres, A. Guarda, N. Moraga, J. Romero
    Experimental and theorical study of LDPE: Evaluation of different food simulants and temperatures
    Food Research International, 44, 3072-3078
  2. M.J. Galotto, A. Torres, A. Guarda, N. Moraga, J. Romero
    Experimental and theorical study of LDPE versus different concentrations of Irganox 1076 and different thickness
    Food Research International 44 566-574
  3. A. Guarda, J.F. Rubilar, J. Miltz, M.J. Galotto
    The Antimicrobial Activity of Microencapsulated Thymol and Carvacrol
    International Journal of Food Microbiology 146 144-150
  4. M.P. Junqueira, M.J. Galotto, X. Valenzuela, C. Dinten, P. Aguirre, J. Miltz
    Perception and view of consumers on food irradiation and the radura symbol
    Radiation Physics and Chemisty 80, 119-122
  5. N. Moraga, A. Torres, A. Guarda, M.J. Galotto
    Non-Newtonian canned liquid food unsteady fluid mechanics and heat transfer prediction for pasteurization and sterilization
    Journal of Food Process Engineering 34, 2000-2025
  6. B. Peoples, F. J. Rodríguez, G. Galland, F. Rabagliati and R. Quijada
    A study of the effect of styrene concentration on the molecular weight of polypropylene produced by metallocene catalysts
    Polym. Int. 60, 839


  1. M.J. Galotto, P. Ulloa, R. Escobar, A. Guarda, R. Gavara, J. Miltz
    Effect of High-Pressure Food Processing on the Mass Transfer Properties of Selected Packaging Materials
    Packag. Technol. Sci. 2010; 23: 253–266; Published Aug/Sep 2010
  2. J.M. Bastías, J. Bermúdez, O. Carrasco, M. Espinoza, M. Muñoz, M.J. Galotto, O. Muñoz
    Determination of Dietary Intake of Total Arsenic, Inorganic Arsenic, and Total Mercury in the Chilean School Meal Program
    Food Science and Technology International 16, 5, 443-450



  1. Polymeric film comprising nanoparticles of copper or silver doped titanium dioxide whose antimicrobicidal activity can be activated by exposure to visible light, useful in the manufacture of food packaging or in surface coatings

    Solicitation date: 01-08-2016
    License Nº.: Solicitud 20161955 (J. Bruna, M. J. Galotto, A. Guarda, F. Rodríguez, A. C. Lopez De Discastillo)
  2. Biodegradable polymer composition with antioxidant and antimicrobial capacity, comprising murta leaf

    Solicitation date: 08-04-2016
    License Nº.: Solicitud 201600817 (C. López de Discastillo, M.J. Galotto, A. Guarda, J. Bruna)


  1. Method of obtaining an adsorber of organic gaseous compounds, based on experimental stages

    Solicitation date: 30-12-2015
    License Nº.: Solicitud N°: 20153777 (F. Rodríguez, M.J. Galotto, A. Guarda, C. Pizarro, J. Bruna)


  1. Development of bionanocomposites with antioxidant and antimicrobial properties obtained from a plastic polymer and an agroindustrial by-product

    Solicitation date: 24-11-2014
    License Nº.: Solicitud 201403190 (M.J. Galotto, J.Bruna, A.Guarda, FJ. Rodríguez)


  1. A process to obtain a film that incorporates antimicrobial agents or natural origin in a polymeric structure

    Solicitation date: 14-03-2011
    License Nº.: Solicitud 20110532 (A.Guarda, X.Valenzuela, A.Ramírez, M.J. Galotto)


  1. A process for obtaining a film comprised of the incorporation of naturally-sourced antimicrobial agents in a polymeric structure to develop packages for increasing the shelf life of refrigerated meat, preferentially refrigerated fresh salmon

    Solicitation date: 03-12-2010
    License Nº.: WO2012073107 A1 (A. Guarda, J. Rubilar, M.J. Galotto)

Maria José Galotto López

(56-2) 7184512, (56-2) 7764796 (Fax)
Laboratorio de Envases. Universidad de Santiago de Chile.
Obispo Manuel Umaña 050, Estación Central, Santiago, Chile.

Investigation Areas:

  • Packaging Technology


Investigadores Titulares

Associate researchers

Technical Support


Associated Institutions: