CEDENNA researchers Dr. Miguel Kiwi (National Prize in Exact Sciences and Board member) and Dr. Felipe Torres, together with Dr. Iván Schuller (CEDENNA international advisor), are the authors of the paper “The impact of the suppression of highly connected protein interactions on the Corona virus infection”, which will soon appear in the prestigious journal Scientific Reports (published by Nature Research).
This work may be key to developing new COVID vaccination strategies, as it shows that there is a specific set of interactions between SARS-CoV-2 and human proteins that, when suppressed, critically modify the structure of the infection. This was predicted with a complex network model and the results were corroborated by several experimental data sources.
The result is high impact considering that the vast majority of vaccination strategies focus exclusively on the role of the Spike protein. Now that infections have started to rise again, and worldwide it is clear that the pandemic is not a thing of the past, this can be very important for developing new vaccination strategies.
